Hello cdone, I am no Dr. I am replying to your question of buspirone (15 mg) and celexa (20 mg) together once a day. I was prescribe the same thing except, I have been taking buspirone (15 mg) for 3 months now and feel better but was still having somewhat panic attacks. Doctors give trusted answers on uses, effects, side-effects, and cautions: Dr. Ali on can i take buspar and lexapro together: Sertraline and cipralex are both ssri antidepressants and do not need to be taken together. Your chance of developing side effects from too much serotonin increases when you take both together. Cipralex is also marketed.